Do not use Oxytrol if you are allergic to oxybutynin, or if you have:

untreated or uncontrolled glaucoma;

a blockage in your digestive tract (stomach or intestines); or

if you have decreased urination or are unable to urinate.

To make sure you can safely use Oxytrol, tell your doctor if you have any of these other conditions:

glaucoma;

liver disease;

kidney disease;

myasthenia gravis;

an enlarged prostate;

an intestinal disorder, such as ulcerative colitis; or

a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.

FDA pregnancy category B. Oxytrol is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether oxybutynin passes into breast milk or if it could harm a nursing baby. Do not use Oxytrol without telling your doctor if you are breast-feeding a baby.

Important safety information: 

Before using Oxytrol, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by oxybutynin.

Tell your doctor about all other medicines you use, especially:

atropine (Donnatal, and others);

belladonna;

dicyclomine (Bentyl);

glycopyrrolate (Robinul);

hyoscyamine (Anaspaz, Cystospaz, Levsin, and others);

mepenzolate (Cantil);

methantheline (Provocholine);

methscopolamine (Pamine);

propantheline (Pro-Banthine);

scopolamine (Transderm-Scop);

an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek); or

antifungal medicine such as itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), miconazole (Oravig), or voriconazole (Vfend).

This list is not complete and other drugs may interact with Oxytrol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction to Oxytrol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Oxytrol and call your doctor at once if you have a serious side effect such as:

fever with hot, dry skin;

uneven heart rate;

pain or burning when you urinate;

urinating less than usual or not at all; or

severe itching, burning, or blistering that does not clear up within several hours after removing the skin patch.

Less serious Oxytrol side effects may include:

mild skin itching, burning, redness, or discoloration where a patch was worn;

dizziness, drowsiness, weakness;

dry eyes, blurred vision;

dry mouth;

warmth, tingling, or redness under your skin;

nausea, vomiting, stomach pain;

constipation or diarrhea;

stuffy nose;

back pain;

feeling restless; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.